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Rottegift (kolekalsiferol) Toksisitet Hos Hester
Rottegift (kolekalsiferol) Toksisitet Hos Hester

Video: Rottegift (kolekalsiferol) Toksisitet Hos Hester

Video: Rottegift (kolekalsiferol) Toksisitet Hos Hester
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Kolekalsiferolforgiftning i hester

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Kolikalciferol (vitamin D3) er den aktive ingrediensen i mange typer rottegift. En høy dose kolikalciferol vil føre til destabilisering av kalsium i kroppen, noe som fører til en tilstand av hyperkalsemi, og til slutt forårsaker forkalkning av kroppens vev og organer. Forhøyede nivåer av kalsium i blodet vil forårsake alvorlig nyreskade.

Noen ganger vil hester komme i kontakt med hestefôr som er forurenset med cholicalciferol, kanskje når giften er lagt i lagringsområder, og som et resultat blir utilsiktet forgiftet. Dette skjer ofte uten vaktmesterens kunnskap. Svelging av denne forbindelsen kan også forekomme når et fôr blandes eller formuleres feil, eller ved overivrig administrering av vitamin D3-tilskudd.

Symptomer

  • Tap av appetitt (anoreksi)
  • Vekttap
  • Depresjon
  • Pustevansker (dyspné)
  • Overdreven tørst (polydipsia) med økt vannforbruk
  • Økt produksjon av urin (polyuri)
  • Svakhet
  • Økt hjertefrekvens
  • Stivhet i lemmen
  • Recumbency
  • Død

Årsaker

  • Svelging av kolikalciferol, vanligvis utilsiktet
  • Innebærer vanligvis forurensning av mat med rottegift

Diagnose

Veterinæren din kan diagnostisere toksisitet for kolikalciferol ved å sende en blodprøve til et laboratorium som måler serumnivåene av forbindelsen. Mer rutinemessig blodarbeid vil vise forhøyede nivåer av fosfor og kalsium, samt tegn på nyreskade.

Behandling

Behandling for forgiftning av kolialciferol vil variere fra sak til sak, avhengig av mengden gift som inntas og på alvorlighetsgraden av symptomene.

Den vanligste tilnærmingen til behandling har vanligvis å gjøre med å begrense mengden vitamin D som tas inn gjennom mat og kosttilskudd. En kalsiumchelator kan gis, da dette vil redusere tarmabsorpsjonen av kalsium. Behandling bør også startes for nyresvikt. Dette er vanligvis støttende pleie og krever administrering av store mengder IV-væsker.

Bo og ledelse

Gjenoppretting fra denne toksikosen kan være langvarig og ofte lite lønnsom, da forkalkning av vev og nyresvikt ikke kan reverseres. Prognosen er bevoktet og eutanasi blir ofte valgt.

Forebygging

Selv om utilsiktet inntak ikke kan forhindres, forekommer denne typen toksikose av og til ved dårlig forvaltning av vitamintilskudd. Før du starter hesten din på noe tilskudd, må du diskutere det med veterinæren.

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